England, who made 12 changes from the starting line-up against Japan, scored 11 tries, including five for 20-year-old winger Arundell that equalled an England record, albeit against the lowest ranked team in the tournament playing at their first World Cup.
Samoa and Japan have five, Argentina four and Chile are yet to register after three defeats.
It was one-way traffic by then and Arundell got his fourth, chipping and gathering his own kick.
Chile showed touches of ambition in the first half but never really threatened and were chasing shadows after the break.
Their coach Pablo Lemoine, who scored a try for Uruguay against England in that 2003 match, said: "I'm not really disappointed, that's reality.
Persons:
Winger Arundell, debutants Smith, Winger Henry Arundell, Steve Borthwick, Arundell, Owen Farrell, Marcus Smith, Smith, Marcus, Theo Dan, Bevan Rodd, Matias Dittus, maul, Dan, Elliot Daly, George Ford, Farrell, England's, Josh Lewsey, Rory Underwood, Daniel Lambert, Ford, Jack Willis, Borthwick, Freddie Steward, Pablo Lemoine, Philip Blenkinsop, Ken Ferris, Clare Fallon
Organizations:
England, LILLE, Japan, Wales, Samoa, Ford, Fiji, France, Thomson
Locations:
France, England, Chile, Marseille, Australia, Fiji, Samoa, Japan, Argentina, flyhalf, Uruguay